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Despite the COVID-19 cases across the world remain high, many countries are re-opening their borders as they move over to the strategy of living with COVID-19. Regular antigen rapid testing has become one of the preventive measures to contain the spread of the coronavirus. Workers from sectors such as construction, food and beverages, logistics, personal care services, etc. are mandated to perform antigen rapid testing on a regular basis. It is therefore important to ensure that the antigen rapid tests are conducted properly and the test results submitted are tampered-free.
Schematic working principle of the PASPORT compared against a conventional antigen rapid test
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Schematic working principle of the PASPORT compared against a conventional antigen rapid test
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Parallel Amplified Saliva rapid POint-of-caRe Test (PASPORT)
Inventors: Danny Jian Hang Tng, Yong Zhang, Melvin Lee Kiang Chua, Jenny Guek Hong Low, Eng Eong Ooi, Khee Chee Soo
In the ongoing COVID-19 pandemic, simple, rapid, point-of-care tests not requiring trained personnel for primary care testing are essential. Saliva-based Antigen Rapid Tests (ARTs) can fill this need, but these tests require overnight-fasted samples; without which, independent studies have demonstrated sensitivities of only 11.7 to 23.1%. Herein, we report a Parallel Amplified Saliva rapid Point-of-caRe Test (PASPORT) with sensitivity above 90%, even with non-fasted samples.